Tuesday, February 18, 2020

Proof reading Essay Example | Topics and Well Written Essays - 500 words

Proof reading - Essay Example The system I developed is more suitable for hot-dry climate area. Now I am looking forward to expanding my experience by getting relevant employment.   I have completed two years job contract as a project engineer for Knowledge Transfer Partner (KTP) Association; this was a joint program between Cooper Technology and University of Nottingham. I have handled a project with a budget of ?200,000, which entailed designing and manufacturing of a new unbound material tester which called Precision Unbound Material Analyzer (PUMA). I carried out this project by myself; starting from market awareness, project management, designing and manufacturing of the product to testing the product, promotion and selling of the product. My educational background is in engineering only, however with the help of my KTP job I have had the opportunity to learn management as well. This opportunity was provided by KTP when they enrolled me in a number of training courses including those for project management , marketing, finance and leadership, software package training course, etc. I have had the opportunity to learn the process to request the UK Patent for the PUMA. Currently, the UK Patent Application No. of the PUMA is 1014471.5.

Monday, February 3, 2020

Gene Silencing Essay Example | Topics and Well Written Essays - 1500 words

Gene Silencing - Essay Example In this research, review of literature pertaining to gene silencing and development of cancer was conducted. The articles were retrieved from PUBMED using suitable terms. Qualitative analysis of the results proved that gene silencing plays a significant role on the development of various cancers. It can thus be concluded that gene silencing through alteration of certain components of tumor suppression genes is one of the means of development of cancers and further research in this aspect may provide information for early detection and novel management of cancers. The soaring rates of cancer has made experts extend their research to ascertain various changes in DNA of certain genes. This is with an intention to know the various mechanisms of evolution of each type of tumor. Understanding of the development of tumor helps in the radical detection of cancer. Recent reports have suggested the importance of both genetic and epigenetic events in the evolution of cancer1. Extensive research has led to the discovery of gene silencing and its role in cancer progression. Various screening methods for cancer with respect to genetic alterations, which are available as of now are not universal tumor markers and thus early detection becomes difficult2. Research has shown that certain alterations like hypermethylation of certain parts of the gene the gene promoters, cause silencing of tumor suppression and this mechanism can be used for universal screening . Currently, further research is in progress to use gene silencing as a molecular marker for early de tection of cancer. Gene silencing is one of the mechanisms of gene regulation during which the expression of gene is either interrupted or suppressed at transcriptional or translational levels. For the past 30 years, researchers have been working on manual methods of gene silencing as a mode of treatment for some diseases. Current research has identified the role of gene silencing in the development of certain